A recent study involving over a thousand children aged 8 to 15 has investigated the effectiveness of different orthokeratology (OK) lens designs in controlling myopia, also known as nearsightedness. Myopia is a growing global concern, predicted to affect nearly 50% of the world’s population by 2050. OK lenses are special contact lenses worn overnight to reshape the cornea and improve daytime vision without glasses or regular contacts, and they are also used to slow down myopia progression in children.
Researchers at several eye hospitals in China compared two main types of OK lens designs: Corneal Refractive Therapy (CRT) lenses and Vision Shaping Treatment (VST) lenses. VST lenses, including brands like Euclid, Alpha, and Hiline, are designed with multiple curves, while CRT lenses are designed with fewer curves. The study followed children wearing one of these four lens types for a year and a half, tracking changes in their refractive error, axial length of the eye (a key measure of myopia progression), and any adverse events.
The study found that while both types of lenses are generally safe, VST lenses demonstrated better efficacy in slowing down myopia progression compared to CRT lenses. Children wearing CRT lenses showed a faster increase in axial length and a higher rate of myopic progression, meaning their nearsightedness worsened more quickly. Specifically, axial length elongation was significantly less with VST lenses. Around 37% of children using CRT lenses experienced fast myopia progression, compared to 20-30% with VST lenses.
Interestingly, CRT lenses showed a slightly better safety profile with a lower overall incidence of adverse events, particularly less corneal staining. Researchers believe this might be related to the material and design of CRT lenses, which may allow for better oxygen permeability to the cornea.
The study suggests that the design of OK lenses can influence how effective they are in controlling myopia. VST lenses, with their multi-curve design, appear to be more effective at slowing myopia progression in children compared to CRT lenses. However, CRT lenses may offer a slight advantage in safety. The findings highlight the importance of personalized lens design in orthokeratology and suggest that further research is needed to optimize lens designs for better myopia control and safety. The study also points to factors like the treatment zone diameter and compression factor of the lenses as potential reasons for the observed differences in efficacy. Experts emphasize that while OK lenses are generally a safe option, careful consideration should be given to lens design and individual patient needs when choosing a myopia management strategy.